Usenamine A
AlkaPlorer ID: AK104074
Synonym: None
IUPAC Name: (2E,9bR)-6-acetyl-2-(1-aminoethylidene)-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione
Structure
SMILES: CC(=O)C1=C2OC3=CC(=O)/C(=C(/C)N)C(=O)[C@]3(C)C2=C(O)C(C)=C1O
InChI: InChI=1S/C18H17NO6/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,22-23H,19H2,1-4H3/b11-7+/t18-/m0/s1
InChIKey: SPBCRTZCVHEBTB-DBEXCURXSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Usnea | Parmeliaceae | Lecanorales | Lecanoromycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 343.33500000000004
TPSA？: 126.92000000000002
MolLogP？: 1.5273199999999998
Number of H-Donors: 3
Number of H-Acceptors: 7
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Leukocyte elastase | Inhibition | 13.26 | % | 10.1016/j.bmc.2013.01.045 |
| Homo sapiens | Leukocyte elastase | Inhibition | 15.32 | % | 10.1016/j.bmc.2013.01.045 |
| None | Unchecked | Inhibition | 20.68 | % | 10.1016/j.bmc.2013.01.045 |
| None | Unchecked | Inhibition | 33.1 | % | 10.1016/j.bmc.2013.01.045 |
| None | Unchecked | Inhibition | 35.32 | % | 10.1016/j.bmc.2013.01.045 |
| None | Unchecked | Inhibition | 41.85 | % | 10.1016/j.bmc.2013.01.045 |
| None | Unchecked | Inhibition | nan | % | 10.1016/j.ejmech.2019.111961 |