Oryzamide A
AlkaPlorer ID: AK104981
Synonym: None
IUPAC Name: (3S,6S,9R,12S,19S)-6-methyl-3,9-bis(2-methylpropyl)-19-[(2S)-octan-2-yl]-12-propan-2-yl-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
Structure
SMILES: CCCCCC[C@H](C)[C@@H]1CC(O)=NCC(O)=N[C@@H](C(C)C)C(O)=N[C@H](CC(C)C)C(O)=N[C@@H](C)C(O)=N[C@@H](CC(C)C)C(=O)O1
InChI: InChI=1S/C33H59N5O7/c1-10-11-12-13-14-22(8)26-17-27(39)34-18-28(40)38-29(21(6)7)32(43)36-24(15-19(2)3)31(42)35-23(9)30(41)37-25(16-20(4)5)33(44)45-26/h19-26,29H,10-18H2,1-9H3,(H,34,39)(H,35,42)(H,36,43)(H,37,41)(H,38,40)/t22-,23-,24+,25-,26-,29-/m0/s1
InChIKey: FUQMTLVDCFTHKB-DRBLLMTBSA-N
Reference
Oryzamides A–E, Cyclodepsipeptides from the Sponge-Derived Fungus <i>Nigrospora oryzae</i> PF18
PubChem CID: 132992352
LOTUS: LTS0206947
NPASS: NPC487155
{NPAtlas: NPA021991
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Nigrospora oryzae | Nigrospora | Apiosporaceae | Xylariales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 637.8630000000002
TPSA？: 189.25
MolLogP？: 6.933400000000007
Number of H-Donors: 5
Number of H-Acceptors: 7
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| None | NON-PROTEIN TARGET | Activity | nan | None | 10.1021/acs.jnatprod.6b00349 |
| None | NON-PROTEIN TARGET | IC50 | 25700.0 | nM | 10.1021/acs.jnatprod.6b00349 |
| None | Unchecked | Inhibition | nan | % | 10.1021/acs.jnatprod.6b00349 |