Tyr-Tyr
AlkaPlorer ID: AK105412
Synonym: 'YY', 'H-Tyr-Tyr-OH', 'di-L-tyrosine', 'N-L-tyrosyl-L-tyrosine', 'Peptide tyrosine-tyrosine', 'Tyrosyltyrosine', 'H-L-Tyr-L-Tyr-OH', 'L-Tyr-L-Tyr', 'Tyr-Tyr'
IUPAC Name: (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Structure
SMILES: N[C@@H](CC1=CC=C(O)C=C1)C(O)=N[C@@H](CC1=CC=C(O)C=C1)C(=O)O
InChI: InChI=1S/C18H20N2O5/c19-15(9-11-1-5-13(21)6-2-11)17(23)20-16(18(24)25)10-12-3-7-14(22)8-4-12/h1-8,15-16,21-22H,9-10,19H2,(H,20,23)(H,24,25)/t15-,16-/m0/s1
InChIKey: JAQGKXUEKGKTKX-HOTGVXAUSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 344.3670000000001
TPSA？: 136.37
MolLogP？: 1.62
Number of H-Donors: 5
Number of H-Acceptors: 5
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Oligopeptide transporter small intestine isoform | EC50 | 60000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | IC50 | 60000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | max activation | 69.0 | % | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | Ratio | 1200.0 | None | 10.1021/jm0511029 |
| Homo sapiens | Tyrosyl-tRNA synthetase | IC50 | 3800.0 | nM | 10.1016/s0960-894x(99)00488-6 |