Leualacin F
AlkaPlorer ID: AK106744
Synonym: None
IUPAC Name: (2R,5S,8S,11S)-11-[(4-hydroxyphenyl)methyl]-2,5,8-tris(2-methylpropyl)-1,7-dioxa-4,10,13-triazacyclohexadecane-3,6,9,12,16-pentone
Structure
SMILES: CC(C)C[C@@H]1N=C(O)[C@@H](CC(C)C)OC(=O)CCN=C(O)[C@H](CC2=CC=C(O)C=C2)N=C(O)[C@H](CC(C)C)OC1=O
InChI: InChI=1S/C30H45N3O8/c1-17(2)13-23-30(39)41-25(15-19(5)6)29(38)32-22(16-20-7-9-21(34)10-8-20)27(36)31-12-11-26(35)40-24(14-18(3)4)28(37)33-23/h7-10,17-19,22-25,34H,11-16H2,1-6H3,(H,31,36)(H,32,38)(H,33,37)/t22-,23-,24+,25-/m0/s1
InChIKey: VETVMJJYHCWIJV-JBXUNAHCSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Hapsidospora irregularis | Hapsidospora | None | Hypocreales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 575.7030000000001
TPSA？: 170.6
MolLogP？: 4.907000000000004
Number of H-Donors: 4
Number of H-Acceptors: 8
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Transient receptor potential cation channel subfamily A member 1 | Activity | None | None | 10.1021/acs.jnatprod.6b00808 |
| Homo sapiens | Transient receptor potential cation channel subfamily M member 8 | Activity | None | None | 10.1021/acs.jnatprod.6b00808 |
| Homo sapiens | Transient receptor potential cation channel subfamily V member 3 | Activity | None | None | 10.1021/acs.jnatprod.6b00808 |
| Homo sapiens | Transient receptor potential cation channel subfamily V member 4 | Activity | None | None | 10.1021/acs.jnatprod.6b00808 |
| Homo sapiens | Vanilloid receptor | Activity | None | None | 10.1021/acs.jnatprod.6b00808 |