6-Methoxykynurenic acid
AlkaPlorer ID: AK106755
Synonym: ''
IUPAC Name: 6-methoxy-4-oxo-1H-quinoline-2-carboxylic acid
Structure
SMILES: COC1=CC=C2NC(C(=O)O)=CC(=O)C2=C1
InChI: InChI=1S/C11H9NO4/c1-16-6-2-3-8-7(4-6)10(13)5-9(12-8)11(14)15/h2-5H,1H3,(H,12,13)(H,14,15)
InChIKey: XQWCILGCSOTHNP-UHFFFAOYSA-N
Reference
New observations on the secondary chemistry of world <i>Ephedra</i> (Ephedraceae)
PubChem CID: 22017520
CAS: 91092-95-4
LOTUS: LTS0176892
COCONUT: CNP0227078
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Ephedra pachyclada | Ephedra | Ephedraceae | Ephedrales | Gnetopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 219.196
TPSA？: 79.39000000000001
MolLogP？: 1.2349
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Glutamate NMDA receptor | Kb | nan | nM | 10.1021/jm00108a002 |
| Rattus norvegicus | Glutamate receptor ionotropic, AMPA | Kb | 87000.0 | nM | 10.1021/jm00108a002 |
| Rattus norvegicus | Glutamate receptor ionotropic, kainate | Kb | 32000.0 | nM | 10.1021/jm00108a002 |
| Rattus norvegicus | Rattus norvegicus | Activity_index | 9.4 | None | 10.1021/jm00207a017 |
| Rattus norvegicus | Rattus norvegicus | ED50 | 82.2 | umol.kg-1 | 10.1021/jm00207a017 |