Val-Val
AlkaPlorer ID: AK108750
Synonym: 'valylvaline', 'H-Val-Val-OH', 'H-L-Val-L-Val-OH', 'V-V', 'L-Val-L-Val'
IUPAC Name: (2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-methylbutanoic acid
Structure
SMILES: CC(C)[C@H](N)C(O)=N[C@H](C(=O)O)C(C)C
InChI: InChI=1S/C10H20N2O3/c1-5(2)7(11)9(13)12-8(6(3)4)10(14)15/h5-8H,11H2,1-4H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1
InChIKey: KRNYOVHEKOBTEF-YUMQZZPRSA-N
Reference
PubChem CID: 107475
CAS: 3918-94-3
LOTUS: LTS0069084
SuperNatural Ⅲ: SN0193506-01
NPASS: NPC321118
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 216.281
TPSA？: 95.91
MolLogP？: 1.0353999999999997
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 0
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Oligopeptide transporter small intestine isoform | EC50 | 70000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | IC50 | 210000.0 | nM | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | max activation | 74.0 | % | 10.1021/jm0511029 |
| Homo sapiens | Oligopeptide transporter small intestine isoform | Ratio | 1000.0 | None | 10.1021/jm0511029 |
| Rattus norvegicus | Tripeptidyl aminopeptidase | Ki | 1670000.0 | nM | 10.1021/jm990226g |
| Saccharomyces cerevisiae | General amino-acid permease GAP1 | Activity | nan | None | 10.1038/nchembio.132 |
| Saccharomyces cerevisiae | General amino-acid permease GAP1 | Inhibition | 15.0 | % | 10.1038/nchembio.132 |
| None | No relevant target | LogP | 2.82 | None | 10.1021/jm00393a031 |
| None | Unchecked | Log 1/T | 1.71 | None | 10.1021/jm00014a022 |
| None | Unchecked | Log 1/T | 1.71 | None | 10.1021/jm00393a031 |