11-hydroxy-2,2-dimethyl-5,10-dihydro-2H-1-oxa-5-azatetraphen-10-one
AlkaPlorer ID: AK114274
Synonym: None
IUPAC Name: 6-hydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
Structure
SMILES: CC1(C)C=CC2=C3NC4=CC=CC=C4C(=O)C3=C(O)C=C2O1
InChI: InChI=1S/C18H15NO3/c1-18(2)8-7-11-14(22-18)9-13(20)15-16(11)19-12-6-4-3-5-10(12)17(15)21/h3-9,20H,1-2H3,(H,19,21)
InChIKey: RPWNPBFZWFWZNJ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Glycosmis pentaphylla | Glycosmis | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 293.32200000000006
TPSA？: 62.32000000000001
MolLogP？: 3.571100000000002
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A549 | IC50 | 6370.0 | nM | 10.1021/np980504z |
| Homo sapiens | CCRF-HSB-2 | IC50 | 3100.0 | nM | 10.1021/np980504z |
| Homo sapiens | TGBC11TKB | IC50 | 2070.0 | nM | 10.1021/np980504z |
| Mus musculus | B16 | IC50 | 5050.0 | nM | 10.1021/np980504z |