3-hydroxy-1,2-dimethoxy-10-methylacridin-9-one
AlkaPlorer ID: AK116265
Synonym: None
IUPAC Name: 3-hydroxy-1,2-dimethoxy-10-methylacridin-9-one
Structure
SMILES: COC1=C(O)C=C2C(=C1OC)C(=O)C1=CC=CC=C1N2C
InChI: InChI=1S/C16H15NO4/c1-17-10-7-5-4-6-9(10)14(19)13-11(17)8-12(18)15(20-2)16(13)21-3/h4-8,18H,1-3H3
InChIKey: WXZWLRMQBKIQRO-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Zanthoxylum leprieurii | Zanthoxylum | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 285.29900000000004
TPSA？: 60.69
MolLogP？: 2.4145000000000003
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A549 | IC50 | 52000.0 | nM | 10.1016/j.bmc.2010.03.040 |
| Homo sapiens | DLD-1 | IC50 | 77000.0 | nM | 10.1016/j.bmc.2010.03.040 |
| None | NON-PROTEIN TARGET | IC50 | 74000.0 | nM | 10.1016/j.bmc.2010.03.040 |