Orixalone A
AlkaPlorer ID: AK117635
Synonym: None
IUPAC Name: 4,8-dimethoxy-1-methyl-3-(3-methyl-2-oxobutyl)quinolin-2-one
Structure
SMILES: COC1=C(CC(=O)C(C)C)C(=O)N(C)C2=C1C=CC=C2OC
InChI: InChI=1S/C17H21NO4/c1-10(2)13(19)9-12-16(22-5)11-7-6-8-14(21-4)15(11)18(3)17(12)20/h6-8,10H,9H2,1-5H3
InChIKey: DIUJWBJYQHUELV-UHFFFAOYSA-N
Reference
PubChem CID: 11278088
CAS: 797788-72-8
LOTUS: LTS0218657
SuperNatural Ⅲ: SN0066879
COCONUT: CNP0234218
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Orixa japonica | Orixa | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 303.35800000000006
TPSA？: 57.53
MolLogP？: 2.3233000000000006
Number of H-Donors: 0
Number of H-Acceptors: 5
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Mesenchymal stem cells | Activity | nan | None | 10.1021/acs.jnatprod.2c00844 |
| Mus musculus | RAW264.7 | Inhibition | 47.3 | % | 10.1021/np0401462 |
| Mus musculus | RAW264.7 | Inhibition | 54.8 | % | 10.1021/np0401462 |