Acidiphilamide A
AlkaPlorer ID: AK118261
Synonym: None
IUPAC Name: (2S,3S)-2-[[(2S)-2-(butanoylamino)-3-phenylpropanoyl]amino]-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-methylpentanamide
Structure
SMILES: CCCC(O)=N[C@@H](CC1=CC=CC=C1)C(O)=N[C@H](C(O)=N[C@H](CO)CC1=CC=CC=C1)[C@@H](C)CC
InChI: InChI=1S/C28H39N3O4/c1-4-12-25(33)30-24(18-22-15-10-7-11-16-22)27(34)31-26(20(3)5-2)28(35)29-23(19-32)17-21-13-8-6-9-14-21/h6-11,13-16,20,23-24,26,32H,4-5,12,17-19H2,1-3H3,(H,29,35)(H,30,33)(H,31,34)/t20-,23-,24-,26-/m0/s1
InChIKey: AMGKYMHWPUSUDA-VIRINCGLSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Rugosus | Dytiscidae | Coleoptera | Insecta | Arthropoda | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 481.6370000000003
TPSA？: 118.0
MolLogP？: 5.285600000000005
Number of H-Donors: 4
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | 26S proteasome | Inhibition | None | % | 10.1021/acs.jnatprod.8b00828 |
| Homo sapiens | HeLa | Activity | None | None | 10.1021/acs.jnatprod.8b00828 |
| Homo sapiens | HeLa | Inhibition | None | % | 10.1021/acs.jnatprod.8b00828 |