Acidiphilamide B
AlkaPlorer ID: AK118262
Synonym: None
IUPAC Name: (2S)-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-methyl-2-[[(2S)-2-(3-methylbutanoylamino)-3-phenylpropanoyl]amino]butanamide
Structure
SMILES: CC(C)CC(O)=N[C@@H](CC1=CC=CC=C1)C(O)=N[C@H](C(O)=N[C@H](CO)CC1=CC=CC=C1)C(C)C
InChI: InChI=1S/C28H39N3O4/c1-19(2)15-25(33)30-24(17-22-13-9-6-10-14-22)27(34)31-26(20(3)4)28(35)29-23(18-32)16-21-11-7-5-8-12-21/h5-14,19-20,23-24,26,32H,15-18H2,1-4H3,(H,29,35)(H,30,33)(H,31,34)/t23-,24-,26-/m0/s1
InChIKey: OAVSVIJLWLCLNU-GNKBHMEESA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Rugosus | Dytiscidae | Coleoptera | Insecta | Arthropoda | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 481.6370000000002
TPSA？: 118.0
MolLogP？: 5.141500000000004
Number of H-Donors: 4
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | 26S proteasome | Inhibition | None | % | 10.1021/acs.jnatprod.8b00828 |
| Homo sapiens | HeLa | Activity | None | None | 10.1021/acs.jnatprod.8b00828 |
| Homo sapiens | HeLa | Inhibition | None | % | 10.1021/acs.jnatprod.8b00828 |