Molecule

Acidiphilamide D

AlkaPlorer ID: AK118268

Synonym: None

IUPAC Name: (2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-(propanoylamino)propanoyl]amino]-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-methylpentanamide

Structure

SMILES: CCC(O)=N[C@@H](CC1=CC=C(O)C=C1)C(O)=N[C@H](C(O)=N[C@H](CO)CC1=CC=CC=C1)[C@@H](C)CC

InChI: InChI=1S/C27H37N3O5/c1-4-18(3)25(27(35)28-21(17-31)15-19-9-7-6-8-10-19)30-26(34)23(29-24(33)5-2)16-20-11-13-22(32)14-12-20/h6-14,18,21,23,25,31-32H,4-5,15-17H2,1-3H3,(H,28,35)(H,29,33)(H,30,34)/t18-,21-,23-,25-/m0/s1

InChIKey: LLNCQMGXHNBIJZ-RCGJGYDGSA-N

Reference

Acidiphilamides A–E, Modified Peptides as Autophagy Inhibitors from an Acidophilic Actinobacterium, <i>Streptacidiphilus rugosus</i>

PubChem CID: 145720802

LOTUS: LTS0210849

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NPAtlas: NPA025028

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
None	Rugosus	Dytiscidae	Coleoptera	Insecta	Arthropoda	Metazoa	Eukaryota

Properties Information

Molecule Weight: 483.60900000000026

TPSA？: 138.23000000000002

MolLogP？: 4.601100000000003

Number of H-Donors: 5

Number of H-Acceptors: 5

RingCount: 2

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	HeLa	Inhibition	None	%	10.1021/acs.jnatprod.8b00828