Karamomycin A
AlkaPlorer ID: AK119016
Synonym: None
IUPAC Name: 2-[(4R)-4-(hydroxymethyl)-4,5-dihydro-1,3-thiazol-2-yl]-4-methoxynaphthalen-1-ol
Structure
SMILES: COC1=CC(C2=N[C@H](CO)CS2)=C(O)C2=CC=CC=C12
InChI: InChI=1S/C15H15NO3S/c1-19-13-6-12(15-16-9(7-17)8-20-15)14(18)11-5-3-2-4-10(11)13/h2-6,9,17-18H,7-8H2,1H3/t9-/m1/s1
InChIKey: OTHAJQJXGMKOCU-SECBINFHSA-N
Reference
Karamomycins A–C: 2-Naphthalen-2-yl-thiazoles from <i>Nonomuraea endophytica</i>
PubChem CID: 145720853
LOTUS: LTS0004891
{NPAtlas: NPA025081
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Nonomuraea | Streptosporangiaceae | Streptosporangiales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 289.35600000000005
TPSA？: 62.05
MolLogP？: 2.408300000000001
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Candida albicans | Candida albicans | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Chlorella sorokiniana | Chlorella sorokiniana | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Chlorella vulgaris | Chlorella vulgaris | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Desmodesmus subspicatus | Desmodesmus subspicatus | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Escherichia coli | Escherichia coli | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Rhizomucor miehei | Rhizomucor miehei | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Staphylococcus aureus | Staphylococcus aureus | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |
| Streptomyces viridochromogenes | Streptomyces viridochromogenes | Activity | None | None | 10.1021/acs.jnatprod.8b00928 |