Marinoquinoline B
AlkaPlorer ID: AK135409
Synonym: None
IUPAC Name: 3-hydroxy-4-(2-methylpropyl)pyrrolo[2,3-c]quinoline
Structure
SMILES: CC(C)CC1=NC2=CC=CC=C2C2=C1N(O)C=C2
InChI: InChI=1S/C15H16N2O/c1-10(2)9-14-15-12(7-8-17(15)18)11-5-3-4-6-13(11)16-14/h3-8,10,18H,9H2,1-2H3
InChIKey: LYDHICJEEQQDAM-UHFFFAOYSA-N
Reference
Marinoquinolines A−F, Pyrroloquinolines from <i>Ohtaekwangia kribbensis</i> (Bacteroidetes)
PubChem CID: 54583213
LOTUS: LTS0258777
NPASS: NPC470111
COCONUT: CNP0370131
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Ohtaekwangia kribbensis | Ohtaekwangia | Fulvivirgaceae | Cytophagales | Cytophagia | Bacteroidota | None | Bacteria |
Properties Information
Molecule Weight: 240.306
TPSA？: 38.05
MolLogP？: 3.625300000000002
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | Activity | nan | None | 10.1021/np100625a |
| Homo sapiens | HUVEC | IC50 | 3.6 | ug.mL-1 | 10.1021/np100625a |
| Homo sapiens | MCF7 | IC50 | 6.5 | ug.mL-1 | 10.1021/np100625a |
| Leishmania donovani | Leishmania donovani | IC50 | 86500.0 | nM | 10.1021/np100625a |
| Micrococcus luteus | Micrococcus luteus | Activity | nan | None | 10.1021/np100625a |
| Mucor hiemalis | Mucor hiemalis | Activity | nan | None | 10.1021/np100625a |
| Mus musculus | L929 | IC50 | 8.0 | ug.mL-1 | 10.1021/np100625a |
| Nocardia sp. | Nocardia sp. | Activity | nan | None | 10.1021/np100625a |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 1800.0 | nM | 10.1021/np100625a |
| Rattus norvegicus | L6 | IC50 | 58700.0 | nM | 10.1021/np100625a |
| Rhodotorula glutinis | Rhodotorula glutinis | Activity | nan | None | 10.1021/np100625a |
| Schizosaccharomyces pombe | Schizosaccharomyces pombe | Activity | nan | None | 10.1021/np100625a |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 45900.0 | nM | 10.1021/np100625a |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 53100.0 | nM | 10.1021/np100625a |
| None | NON-PROTEIN TARGET | IC50 | 5.0 | ug.mL-1 | 10.1021/np100625a |