Molecule

Fosthiazate

AlkaPlorer ID: AK135910

Synonym: None

IUPAC Name: 3-[butan-2-ylsulfanyl(ethoxy)phosphoryl]-1,3-thiazolidin-2-one

Structure

SMILES: CCOP(=O)(SC(C)CC)N1CCSC1=O

InChI: InChI=1S/C9H18NO3PS2/c1-4-8(3)16-14(12,13-5-2)10-6-7-15-9(10)11/h8H,4-7H2,1-3H3

InChIKey: DUFVKSUJRWYZQP-UHFFFAOYSA-N

Reference

Nematicidal Activity of 2-Thiophenecarboxaldehyde and Methylisothiocyanate from Caper (<i>Capparis spinosa</i>) against <i>Meloidogyne incognita</i>

PubChem CID: 91758

CAS: 6294-01-5

LOTUS: LTS0108661

NPASS: NPC470234

COCONUT: CNP0281378

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Capparis spinosa	Capparis	Capparaceae	Brassicales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 283.355

TPSA？: 46.61

MolLogP？: 3.831500000000003

Number of H-Donors: 0

Number of H-Acceptors: 5

RingCount: 1

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	Androgen Receptor	Potency	1412.5	nM	None
Homo sapiens	Glucocorticoid receptor	Potency	15848.9	nM	None
Meloidogyne incognita	Meloidogyne incognita	Activity	0.0	%	10.1584/jpestics.22.187
Meloidogyne incognita	Meloidogyne incognita	Activity	nan	None	10.1016/j.cropro.2009.01.011
Meloidogyne incognita	Meloidogyne incognita	EC100	3.0	mg/L	10.1021/jf305164m
Meloidogyne incognita	Meloidogyne incognita	EC50	0.079	ppm	10.1584/jpestics.22.187
Meloidogyne incognita	Meloidogyne incognita	EC50	0.4	ug.mL-1	10.1021/jf1025345
Meloidogyne incognita	Meloidogyne incognita	EC50	0.4	ug.mL-1	10.1021/jf302075w
Meloidogyne incognita	Meloidogyne incognita	EC50	0.4	ug.mL-1	10.1021/jf3038874
Meloidogyne incognita	Meloidogyne incognita	EC50	0.4	ug.mL-1	10.1021/jf305164m
Meloidogyne incognita	Meloidogyne incognita	EC50	2.339	ppm	10.1584/jpestics.22.187
Meloidogyne incognita	Meloidogyne incognita	EC50	3.3	ug.mL-1	10.1021/jf1025345
Meloidogyne incognita	Meloidogyne incognita	EC50	3.3	ug.mL-1	10.1021/jf302075w
Meloidogyne incognita	Meloidogyne incognita	EC50	29.6	ppm	10.1584/jpestics.22.187
Meloidogyne javanica	Meloidogyne javanica	EC50	15.9	ug.mL-1	10.1021/jf2044586
Meloidogyne javanica	Meloidogyne javanica	EC50	25.0	ug.mL-1	10.1021/jf2044586
Musca domestica	Acetylcholinesterase	IC50	1000000.0	nM	10.1584/jpestics.22.187
Musca domestica	Musca domestica	Activity	0.108	ug	10.1584/jpestics.22.187
Musca domestica	Musca domestica	Activity	1.945	ug	10.1584/jpestics.22.187
Musca domestica	Musca domestica	Activity	18.0	ug	10.1584/jpestics.22.187
Mus musculus	Mus musculus	LD50	127.0	mg.kg-1	10.1584/jpestics.22.187
Myzus persicae	Myzus persicae	Activity	90.0	%	10.1584/jpestics.22.187
Myzus persicae	Myzus persicae	LC50	4.06	ppm	10.1584/jpestics.22.187
Myzus persicae	Myzus persicae	LC50	13.2	ppm	10.1584/jpestics.22.187
Myzus persicae	Myzus persicae	LC50	53.7	ppm	10.1584/jpestics.22.187
Rattus norvegicus	Nuclear receptor subfamily 1 group I member 2	Potency	39810.7	nM	None
Solanum lycopersicum	Solanum lycopersicum	Activity	nan	None	10.1016/j.cropro.2009.01.011
Tetranychus urticae	Tetranychus urticae	Activity	90.0	%	10.1584/jpestics.22.187
Tetranychus urticae	Tetranychus urticae	LC50	22.4	ppm	10.1584/jpestics.22.187
Tetranychus urticae	Tetranychus urticae	LC50	35.7	ppm	10.1584/jpestics.22.187
Tetranychus urticae	Tetranychus urticae	LC50	800.0	ppm	10.1584/jpestics.22.187
None	Molecular identity unknown	Potency	15848.9	nM	None
None	No relevant target	pKa	11.6	None	10.1584/jpestics.22.187