7-desmethyl-6-methylbostrycoidin
AlkaPlorer ID: AK145205
Synonym: None
IUPAC Name: 7,9-dihydroxy-6-methoxy-3-methylbenzo[g]isoquinoline-5,10-dione
Structure
SMILES: COC1=C(O)C=C(O)C2=C1C(=O)C1=CC(C)=NC=C1C2=O
InChI: InChI=1S/C15H11NO5/c1-6-3-7-8(5-16-6)14(20)11-9(17)4-10(18)15(21-2)12(11)13(7)19/h3-5,17-18H,1-2H3
InChIKey: OHNMVGHHHMYTJO-UHFFFAOYSA-N
Reference
Cytotoxic Naphthoquinone and Azaanthraquinone Derivatives from an Endophytic <i>Fusarium solani</i>
PubChem CID: 132967559
LOTUS: LTS0148975
COCONUT: CNP0073188
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Fusarium solani | Fusarium | Nectriaceae | Hypocreales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 285.255
TPSA？: 96.72
MolLogP？: 1.5852199999999994
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HeLa | IC50 | 710.0 | nM | 10.1021/acs.jnatprod.6b00610 |
| Homo sapiens | MDA-MB-231 | IC50 | 730.0 | nM | 10.1021/acs.jnatprod.6b00610 |
| Homo sapiens | MIA PaCa-2 | IC50 | 640.0 | nM | 10.1021/acs.jnatprod.6b00610 |
| Homo sapiens | NCI-H1975 | IC50 | 340.0 | nM | 10.1021/acs.jnatprod.6b00610 |
| Homo sapiens | WI-38 | IC50 | 6420.0 | nM | 10.1021/acs.jnatprod.6b00610 |