Protoemetinol
AlkaPlorer ID: AK145515
Synonym: ''
IUPAC Name: 2-[(2R,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]ethanol
Structure
SMILES: CC[C@H]1CN2CCC3=CC(OC)=C(OC)C=C3[C@@H]2C[C@@H]1CCO
InChI: InChI=1S/C19H29NO3/c1-4-13-12-20-7-5-15-10-18(22-2)19(23-3)11-16(15)17(20)9-14(13)6-8-21/h10-11,13-14,17,21H,4-9,12H2,1-3H3/t13-,14-,17-/m0/s1
InChIKey: HZYOXXWBFOLHRJ-ZQIUZPCESA-N
Reference
Two <i>Alangium</i> Alkaloids from <i>Alangium </i><i>l</i><i>amarckii</i>
PubChem CID: 11162971
LOTUS: LTS0256846
SuperNatural Ⅲ: SN0140036-01
NPASS: NPC229031
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Alangium salviifolium | Alangium | Cornaceae | Cornales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 319.4450000000001
TPSA？: 41.93000000000001
MolLogP？: 3.0315000000000016
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A549 | IC50 | 300.0 | nM | 10.1021/acs.jnatprod.9b00670 |
| Homo sapiens | HeLa | IC50 | 1200.0 | nM | 10.1021/acs.jnatprod.9b00670 |
| Homo sapiens | SK-OV-3 | IC50 | 100.0 | nM | 10.1021/acs.jnatprod.9b00670 |