Naucleofficine D
AlkaPlorer ID: AK155477
Synonym: '(-)-Naucleofficine D'
IUPAC Name: (1S,15S,16R,19E,20R)-19-ethylidene-16-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8-tetraen-14-one
Structure
SMILES: C/C=C1/CO[C@@H](O)[C@H]2C(=O)N3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@@H]12
InChI: InChI=1S/C20H22N2O3/c1-2-11-10-25-20(24)17-14(11)9-16-18-13(7-8-22(16)19(17)23)12-5-3-4-6-15(12)21-18/h2-6,14,16-17,20-21,24H,7-10H2,1H3/b11-2-/t14-,16-,17+,20+/m0/s1
InChIKey: ILRJXCUWXJKRSS-IAVPRRAMSA-N
Reference
Indole alkoloids from Nauclea officinalis with weak antimalarial activity
PubChem CID: 24862703
LOTUS: LTS0201700
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Nauclea officinalis | Nauclea | Rubiaceae | Gentianales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 338.40700000000004
TPSA？: 65.56
MolLogP？: 2.5247
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|