4-ethenyl-4,8,8-trimethyl-15-(2-methylbut-3-en-2-yl)-14-azatetracyclo[7.6.1.0²,?.0¹³,¹?]hexadeca-1(15),9(16),10,12-tetraene-3-carbonitrile
AlkaPlorer ID: AK157999
Synonym: None
IUPAC Name: (2R,3R,4R,7S)-4-ethenyl-4,8,8-trimethyl-15-(2-methylbut-3-en-2-yl)-14-azatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),9(16),10,12-tetraene-3-carbonitrile
Structure
SMILES: C=CC(C)(C)C1=C2C3=C(C=CC=C3N1)C(C)(C)[C@H]1CC[C@](C)(C=C)[C@H](C#N)[C@H]21
InChI: InChI=1S/C26H32N2/c1-8-24(3,4)23-22-20-17(13-14-26(7,9-2)18(20)15-27)25(5,6)16-11-10-12-19(28-23)21(16)22/h8-12,17-18,20,28H,1-2,13-14H2,3-7H3/t17-,18+,20+,26-/m0/s1
InChIKey: FVLJNWUXPRLMPE-QPHCBKPXSA-N
Reference
Antimicrobial Ambiguines from the Cyanobacterium <i>Fischerella</i> sp. Collected in Israel
PubChem CID: 44419568
LOTUS: LTS0030637
NPASS: NPC477134
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Fischerella sp. | Fischerella | Hapalosiphonaceae | Nostocales | Cyanophyceae | Cyanobacteriota | None | Bacteria |
Properties Information
Molecule Weight: 372.55600000000015
TPSA？: 39.58
MolLogP？: 6.748380000000006
Number of H-Donors: 1
Number of H-Acceptors: 1
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 1.25 | ug.mL-1 | 10.1021/np060495r |
| Candida albicans | Candida albicans | MIC | 6.25 | ug.mL-1 | 10.1021/np060495r |
| Escherichia coli | Escherichia coli | MIC | 10.0 | ug.mL-1 | 10.1021/np060495r |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | MIC | 5.0 | ug.mL-1 | 10.1021/np060495r |
| None | NON-PROTEIN TARGET | MIC | 0.625 | ug.mL-1 | 10.1021/np060495r |