nor-rhazinicine
AlkaPlorer ID: AK165413
Synonym: None
IUPAC Name: (12S)-12-ethyl-8,15-diazatetracyclo[10.5.1.02,7.015,18]octadeca-1(18),2,4,6,16-pentaene-9,14-dione
Structure
SMILES: CC[C@@]12CCC(O)=NC3=CC=CC=C3C3=C1N(C=C3)C(=O)C2
InChI: InChI=1S/C18H18N2O2/c1-2-18-9-7-15(21)19-14-6-4-3-5-12(14)13-8-10-20(17(13)18)16(22)11-18/h3-6,8,10H,2,7,9,11H2,1H3,(H,19,21)/t18-/m0/s1
InChIKey: COHWSGIPTWGSIO-SFHVURJKSA-N
Reference
Rhazinilam–Leuconolam–Leuconoxine Alkaloids from <i>Leuconotis griffithii</i>
PubChem CID: 71714596
LOTUS: LTS0055497
NPASS: NPC64436
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 294.3540000000001
TPSA？: 54.59
MolLogP？: 4.228600000000003
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | KB | IC50 | 12.0 | ug.mL-1 | 10.1021/np400214y |