8-Hydroxycanthin-6-one
AlkaPlorer ID: AK169719
Synonym: ''
IUPAC Name: 14-hydroxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one
Structure
SMILES: O=C1C=CC2=NC=CC3=C2N1C1=C3C=CC=C1O
InChI: InChI=1S/C14H8N2O2/c17-11-3-1-2-8-9-6-7-15-10-4-5-12(18)16(13(9)10)14(8)11/h1-7,17H
InChIKey: WBFKHEDOTNJGJF-UHFFFAOYSA-N
Reference
Plant Anticancer Agents XXXV. Further Constituents of<i>Simaba multiflora</i>,
PubChem CID: 6455362
CAS: 66762-19-4
LOTUS: LTS0059999
SuperNatural Ⅲ: SN0405624
COCONUT: CNP0242986
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 236.23
TPSA？: 54.60000000000001
MolLogP？: 2.1443
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | CNE-2 | IC50 | 13.43 | ug.mL-1 | 10.1016/j.ejmech.2021.113688 |
| Mycobacterium | Mycobacterium | MIC | 2.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 8.0 | ug.mL-1 | 10.1016/j.ejmech.2017.04.003 |