1-methyl-3-acetyl-indole
AlkaPlorer ID: AK182853
Synonym: None
IUPAC Name: 1-(1-methylindol-3-yl)ethanone
Structure
SMILES: CC(=O)C1=CN(C)C2=CC=CC=C12
InChI: InChI=1S/C11H11NO/c1-8(13)10-7-12(2)11-6-4-3-5-9(10)11/h3-7H,1-2H3
InChIKey: HYLFRICFKVJJOZ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 173.215
TPSA？: 22.0
MolLogP？: 2.3809000000000005
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | CREB-binding protein | Delta Tm | 2.9 | degrees C | 10.1016/j.bmcl.2017.04.001 |
| Homo sapiens | CREB-binding protein | IC50 | nan | None | 10.1016/j.bmcl.2017.04.001 |
| Homo sapiens | CREB-binding protein | Inhibition | 31.0 | % | 10.1016/j.bmcl.2017.04.001 |
| Homo sapiens | CREB-binding protein | Kd | nan | None | 10.1016/j.bmcl.2017.04.001 |
| Homo sapiens | Histone acetyltransferase p300 | Delta Tm | 2.6 | degrees C | 10.1016/j.bmcl.2017.04.001 |