Molecule

(2S,4S)-2-amino-4-(hydroxymethyl)pentanedioic acid

AlkaPlorer ID: AK192010

Synonym: None

IUPAC Name: (2S,4S)-2-amino-4-(hydroxymethyl)pentanedioic acid

Structure

SMILES: N[C@@H](C[C@@H](CO)C(=O)O)C(=O)O

InChI: InChI=1S/C6H11NO5/c7-4(6(11)12)1-3(2-8)5(9)10/h3-4,8H,1-2,7H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChIKey: GZEURHPPKFNBRU-IMJSIDKUSA-N

Reference

Metabolites from the Fungal Endophyte <i>Aspergillus austroafricanus</i> in Axenic Culture and in Fungal–Bacterial Mixed Cultures

PubChem CID: 24905651

SuperNatural Ⅲ: SN0119292-01

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain

Properties Information

Molecule Weight: 177.156

TPSA？: 120.85

MolLogP？: -1.5184999999999995

Number of H-Donors: 4

Number of H-Acceptors: 4

RingCount: 0

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	Excitatory amino acid transporter 1	IC50	3000000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 1	IC50	3162277.66	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 1	Ki	3000000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 1	Ki	3162277.66	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 2	IC50	300000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 2	IC50	316227.77	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 2	Ki	125892.54	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 2	Ki	140000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 3	IC50	3000000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 3	IC50	3162277.66	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 3	Ki	3000.0	nM	10.1021/jm800091e
Homo sapiens	Excitatory amino acid transporter 3	Ki	3162277.66	nM	10.1021/jm800091e
Rattus norvegicus	Glutamate NMDA receptor	Ki	15000.0	nM	10.1021/jm800092x
Rattus norvegicus	Glutamate NMDA receptor	Ki	15135.61	nM	10.1021/jm800092x
Rattus norvegicus	Glutamate receptor ionotropic kainate 1	Ki	nan	None	10.1021/jm800092x
Rattus norvegicus	Glutamate receptor ionotropic kainate 2	Ki	nan	None	10.1021/jm800092x
Rattus norvegicus	Glutamate receptor ionotropic kainate 3	Ki	nan	None	10.1021/jm800092x
None	Unchecked	IC50	239.88	nM	10.1021/jm800092x
None	Unchecked	IC50	240.0	nM	10.1021/jm800092x
None	Unchecked	IC50	44000.0	nM	10.1021/jm800092x
None	Unchecked	IC50	44668.36	nM	10.1021/jm800092x