4,5,7-trimethyl-6-(piperidine-1-sulfonyl)-1,2-dihydroquinolin-2-one
AlkaPlorer ID: AK204804
Synonym: None
IUPAC Name: 4,5,7-trimethyl-6-piperidin-1-ylsulfonyl-1H-quinolin-2-one
Structure
SMILES: CC1=C(S(=O)(=O)N2CCCCC2)C(C)=C2C(C)=CC(=O)NC2=C1
InChI: InChI=1S/C17H22N2O3S/c1-11-10-15(20)18-14-9-12(2)17(13(3)16(11)14)23(21,22)19-7-5-4-6-8-19/h9-10H,4-8H2,1-3H3,(H,18,20)
InChIKey: GEMHSANWHNDBFW-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 334.441
TPSA？: 70.24000000000001
MolLogP？: 2.6279600000000007
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | Inhibition | -7.0 | % | 10.6019/CHEMBL4888484 |
| Plasmodium falciparum | Plasmodium falciparum | Z score | 0.84 | None | 10.6019/CHEMBL4888484 |