2-[(2-amino-9H-purin-6-yl)amino]acetic acid
AlkaPlorer ID: AK210573
Synonym: None
IUPAC Name: 2-[(2-amino-7H-purin-6-yl)amino]acetic acid
Structure
SMILES: NC1=NC(NCC(=O)O)=C2N=CNC2=N1
InChI: InChI=1S/C7H8N6O2/c8-7-12-5(9-1-3(14)15)4-6(13-7)11-2-10-4/h2H,1H2,(H,14,15)(H4,8,9,10,11,12,13)
InChIKey: VXUGGBKXRNSOPC-UHFFFAOYSA-N
Reference
Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression
Effects of Naringin on Hydrogen Peroxide-Induced Cytotoxicity and Apoptosis in P388 Cells
Inhibition of Cell Growth and VEGF Expression in Ovarian Cancer Cells by Flavonoids
PubChem CID: 71826867
COCONUT: CNP0294661
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
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Properties Information
Molecule Weight: 208.181
TPSA？: 129.81
MolLogP？: -0.5684000000000002
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mycobacterium avium | Mycobacterium avium | MIC | nan | None | 10.1016/j.bmcl.2016.04.017 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC | 12.5 | ug.mL-1 | 10.1016/j.bmcl.2016.04.017 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC | nan | None | 10.1016/j.bmcl.2016.04.017 |
| Mycolicibacter terrae | Mycolicibacter terrae | MIC | nan | None | 10.1016/j.bmcl.2016.04.017 |
| None | ADMET | IC50 | nan | None | 10.1016/j.bmcl.2016.04.017 |