7-hydroxy-3-methoxy-6-methyl-4,9-dihydro-1H-carbazole-1,4-dione
AlkaPlorer ID: AK237164
Synonym: None
IUPAC Name: 7-hydroxy-3-methoxy-6-methyl-9H-carbazole-1,4-dione
Structure
SMILES: COC1=CC(=O)C2=C(C1=O)C1=CC(C)=C(O)C=C1N2
InChI: InChI=1S/C14H11NO4/c1-6-3-7-8(4-9(6)16)15-13-10(17)5-11(19-2)14(18)12(7)13/h3-5,15-16H,1-2H3
InChIKey: VREJGEPSCUUWMS-UHFFFAOYSA-N
Reference
Carbazole alkaloids from Clausena excavata and their biological activity
PubChem CID: 44317062
LOTUS: LTS0231845
COCONUT: CNP0293427
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Clausena excavata | Clausena | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 257.24499999999995
TPSA？: 79.39000000000001
MolLogP？: 2.09122
Number of H-Donors: 2
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HCT-8 | IC50 | 0.92 | ug.mL-1 | 10.1016/S0960-894X(01)80397-8 |
| Homo sapiens | RPMI-7951 | IC50 | 0.22 | ug.mL-1 | 10.1016/S0960-894X(01)80397-8 |
| Homo sapiens | TE-671 | IC50 | 3.82 | ug.mL-1 | 10.1016/S0960-894X(01)80397-8 |