4-(5-methoxy-2-phenyl-1-benzofuran-3-carbonyl)morpholine
AlkaPlorer ID: AK241869
Synonym: None
IUPAC Name: (5-methoxy-2-phenyl-1-benzofuran-3-yl)-morpholin-4-ylmethanone
Structure
SMILES: COC1=CC=C2OC(C3=CC=CC=C3)=C(C(=O)N3CCOCC3)C2=C1
InChI: InChI=1S/C20H19NO4/c1-23-15-7-8-17-16(13-15)18(20(22)21-9-11-24-12-10-21)19(25-17)14-5-3-2-4-6-14/h2-8,13H,9-12H2,1H3
InChIKey: QKTMFZFUTOCIJS-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 337.37500000000017
TPSA？: 51.91
MolLogP？: 3.5808000000000018
Number of H-Donors: 0
Number of H-Acceptors: 4
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus anthracis | Anthrax lethal factor | Potency | 10000.0 | nM | None |
| Bacillus subtilis (strain 168) | ATP-dependent Clp protease proteolytic subunit | Potency | 28183.8 | nM | None |
| Homo sapiens | 15-hydroxyprostaglandin dehydrogenase [NAD+] | Potency | 35481.3 | nM | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 28183.8 | nM | None |
| Homo sapiens | Ataxin-2 | Potency | 19952.6 | nM | None |
| Homo sapiens | DNA-(apurinic or apyrimidinic site) lyase | Potency | 6309.6 | nM | None |
| Homo sapiens | DNA polymerase eta | Potency | 89125.1 | nM | None |
| Homo sapiens | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Potency | 31622.8 | nM | None |
| Homo sapiens | Glucagon-like peptide 1 receptor | Potency | 7943.3 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 4466.8 | nM | None |
| Homo sapiens | HepG2 | Potency | 3162.3 | nM | None |
| Homo sapiens | Lysine-specific demethylase 4D-like | Potency | 31622.8 | nM | None |
| Homo sapiens | Microtubule-associated protein tau | Potency | 3162.3 | nM | None |
| Homo sapiens | TAR DNA-binding protein 43 | Potency | 12589.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 12995.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 16360.1 | nM | None |
| Influenza A virus | Nonstructural protein 1 | Potency | 11220.2 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 18526.0 | nM | None |
| Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Potency | 39810.7 | nM | None |
| Sus scrofa | Trypsin | AC50 | 4548.0 | nM | None |
| None | Unchecked | Potency | 31622.8 | nM | None |