6,8,9,11-Tetrahydro-7H-pyrido[2,1-b]quinazoline
AlkaPlorer ID: AK249408
Synonym: 6,7,8,9-Tetrahydro-11H-pyrido[2,1-b]quinazoline
IUPAC Name: 7,8,9,11-tetrahydro-6H-pyrido[2,1-b]quinazoline
Structure
SMILES: C1=CC=C2N=C3CCCCN3CC2=C1
InChI: InChI=1S/C12H14N2/c1-2-6-11-10(5-1)9-14-8-4-3-7-12(14)13-11/h1-2,5-6H,3-4,7-9H2
InChIKey: PZRHMLTUOQZGFU-UHFFFAOYSA-N
Reference
6,7,8,9-Tetrahydropyridoquinazolines, a new class of alkaloids from Mackinlaya species (Araliaceae)
PubChem CID: 6420076
LOTUS: LTS0214411
SuperNatural Ⅲ: SN0299466
COCONUT: CNP0168839
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Mackinlaya | Apiaceae | Apiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 186.258
TPSA？: 15.6
MolLogP？: 2.716100000000001
Number of H-Donors: 0
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Acetylcholinesterase | IC50 | 3660.0 | nM | 10.1016/0960-894X(96)00102-3 |
| Rattus norvegicus | Acetylcholinesterase | IC50 | 100000.0 | nM | 10.1016/0960-894X(96)00102-3 |