2-(1H-indol-3-yl)-2-oxoacetic acid
AlkaPlorer ID: AK253935
Synonym: None
IUPAC Name: 2-(1H-indol-3-yl)-2-oxoacetic acid
Structure
SMILES: O=C(O)C(=O)C1=CNC2=CC=CC=C12
InChI: InChI=1S/C10H7NO3/c12-9(10(13)14)7-5-11-8-4-2-1-3-6(7)8/h1-5,11H,(H,13,14)
InChIKey: DWLVFWDCSFTDOD-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Polyandrocarpa zorritensis | Polyandrocarpa | Styelidae | Stolidobranchia | Ascidiacea | Chordata | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 189.17
TPSA？: 70.16
MolLogP？: 1.4352
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Candida albicans | Isocitrate lyase | IC50 | 100.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Escherichia coli | Escherichia coli | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Homo sapiens | Protein-tyrosine phosphatase 1B | IC50 | 390000.0 | nM | 10.1016/s0960-894x(01)00325-0 |
| Micrococcus luteus | Micrococcus luteus | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Proteus vulgaris | Proteus vulgaris | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Salmonella enterica subsp. enterica serovar Typhimurium | Salmonella typhimurium | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Staphylococcus aureus | Sortase A | IC50 | 13.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |
| Staphylococcus aureus | Sortase A | IC50 | 69000.0 | nM | 10.1016/j.bmcl.2010.10.029 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 200.0 | ug.mL-1 | 10.1016/j.bmcl.2010.10.029 |