APNE
AlkaPlorer ID: AK258062
Synonym: None
IUPAC Name: naphthalen-2-yl 2-acetamido-3-phenylpropanoate
Structure
SMILES: CC(=O)NC(CC1=CC=CC=C1)C(=O)OC1=CC=C2C=CC=CC2=C1
InChI: InChI=1S/C21H19NO3/c1-15(23)22-20(13-16-7-3-2-4-8-16)21(24)25-19-12-11-17-9-5-6-10-18(17)14-19/h2-12,14,20H,13H2,1H3,(H,22,23)
InChIKey: BBXRRTJNJCPGBU-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 333.38700000000006
TPSA？: 55.400000000000006
MolLogP？: 3.492600000000002
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 | Potency | 7943.3 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 1000.0 | nM | None |
| Homo sapiens | Rac GTPase-activating protein 1 | IC50 | 39710.0 | nM | None |
| None | Unchecked | IC50 | 100000.0 | nM | None |
| None | Unchecked | Potency | 1778.3 | nM | None |
| None | Unchecked | Potency | 7079.5 | nM | None |