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name Structure Reference Source Properties Activities Metabolism

7-amino-8-(2,4-dihydroxy-6-methylphenyl)-1,9-dimethyl-3H-phenoxazin-3-one

AlkaPlorer ID: AK262423

Synonym: None

IUPAC Name: 7-amino-8-(2,4-dihydroxy-6-methylphenyl)-1,9-dimethylphenoxazin-3-one

Structure

SMILES: CC1=CC(=O)C=C2OC3=CC(N)=C(C4=C(C)C=C(O)C=C4O)C(C)=C3N=C21

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InChI: InChI=1S/C21H18N2O4/c1-9-4-12(24)6-15(26)18(9)19-11(3)21-17(8-14(19)22)27-16-7-13(25)5-10(2)20(16)23-21/h4-8,24,26H,22H2,1-3H3

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InChIKey: NNZHGEUZKBYASA-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 362.3850000000001

TPSA？: 109.58

MolLogP？: 3.878460000000002

Number of H-Donors: 3

Number of H-Acceptors: 6

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Potency 50118.7 nM None
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Potency 19905.4 nM None
Homo sapiens Arachidonate 15-lipoxygenase Potency 5011.9 nM None
Homo sapiens Arachidonate 15-lipoxygenase, type II Potency 7943.3 nM None
Homo sapiens Bloom syndrome protein Potency 15848.9 nM None
Homo sapiens Bloom syndrome protein Potency 20434.0 nM None
Homo sapiens Breast cancer type 1 susceptibility protein Potency 39810.7 nM None
Homo sapiens Cytochrome P450 3A4 Potency 39810.7 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 14125.4 nM None
Homo sapiens DNA polymerase kappa Potency 4466.8 nM None
Homo sapiens Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Potency 7943.3 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 12589.3 nM None
Homo sapiens Lysine-specific demethylase 4D-like Potency 8912.5 nM None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 14125.4 nM None
Homo sapiens Microtubule-associated protein tau Potency 6309.6 nM None
Homo sapiens Microtubule-associated protein tau Potency 14125.4 nM None
Homo sapiens Microtubule-associated protein tau Potency 22387.2 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 8876.6 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 8912.5 nM None
Homo sapiens Thyroid hormone receptor beta-1 Potency 2238.7 nM None
Homo sapiens Thyroid hormone receptor beta-1 Potency 6309.6 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 46945.0 nM None
Homo sapiens Ubiquitin carboxyl-terminal hydrolase 1 Potency 56234.1 nM None
Homo sapiens Vitamin D receptor Potency 35481.3 nM None
Photuris pennsylvanica Luciferase Potency 14125.4 nM None
Rattus norvegicus Inositol monophosphatase 1 Potency 11220.2 nM None
None Unchecked Ki 35000.0 nM 10.1016/j.ejmech.2016.04.008
None Unchecked Potency 70794.6 nM None

Metabolism Information