1-(2-methoxyphenyl)pyrrole-2,5-dione
AlkaPlorer ID: AK262929
Synonym: None
IUPAC Name: 1-(2-methoxyphenyl)pyrrole-2,5-dione
Structure
SMILES: COC1=CC=CC=C1N1C(=O)C=CC1=O
InChI: InChI=1S/C11H9NO3/c1-15-9-5-3-2-4-8(9)12-10(13)6-7-11(12)14/h2-7H,1H3
InChIKey: LJDGDRYFCIHDPX-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 203.197
TPSA？: 46.61
MolLogP？: 1.1245999999999998
Number of H-Donors: 0
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Anandamide amidohydrolase | IC50 | 500000.0 | nM | 10.1021/jm900461w |
| Homo sapiens | HepG2-CD81 | HEPG2TOX ASSAY - CC50 | 16.2 | uM | 10.1126/science.aat9446 |
| Homo sapiens | HepG2-CD81 | HEPG2TOX ASSAY - CC90 | 16.2 | uM | 10.1126/science.aat9446 |
| Homo sapiens | Monoglyceride lipase | IC50 | 6920.0 | nM | 10.1021/jm900461w |
| Plasmodium berghei | Plasmodium berghei | LUCIFERASE EXPRESSION CONTROL - IC50 | 16.2 | uM | 10.1126/science.aat9446 |
| Plasmodium berghei | Plasmodium berghei | LUCIFERASE EXPRESSION CONTROL - IC90 | 16.2 | uM | 10.1126/science.aat9446 |
| Plasmodium berghei | Plasmodium berghei | LUCIFERASE INFECTION ASSAY - IC50 | 16.2 | uM | 10.1126/science.aat9446 |
| Plasmodium berghei | Plasmodium berghei | LUCIFERASE INFECTION ASSAY - IC90 | 16.2 | uM | 10.1126/science.aat9446 |
| None | Unchecked | Ratio IC50 | 78.0 | None | 10.1021/jm900461w |