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1,3-diphenylpyrazole-4-carbaldehyde

AlkaPlorer ID: AK267966

Synonym: None

IUPAC Name: 1,3-diphenylpyrazole-4-carbaldehyde

Structure

SMILES: O=CC1=CN(C2=CC=CC=C2)N=C1C1=CC=CC=C1

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InChI: InChI=1S/C16H12N2O/c19-12-14-11-18(15-9-5-2-6-10-15)17-16(14)13-7-3-1-4-8-13/h1-12H

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InChIKey: LZGBMIZREYTWRI-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 248.285

TPSA？: 34.89

MolLogP？: 3.3518000000000017

Number of H-Donors: 0

Number of H-Acceptors: 3

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bos taurus Mitochondrial peptide methionine sulfoxide reductase IC50 155073.0 nM None
Escherichia coli K-12 Beta-lactamase AmpC Potency 1258.9 nM None
Homo sapiens A549 IC50 13710.0 nM 10.1016/j.ejmech.2015.07.031
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 20587.8 nM None
Homo sapiens Chromobox protein homolog 1 Potency 89125.1 nM None
Homo sapiens COX-1/COX-2 Ratio IC50 0.008 None 10.1039/d1md00280e
Homo sapiens Cyclooxygenase-2 IC50 17.0 nM 10.1039/d1md00280e
Homo sapiens Glucagon-like peptide 1 receptor Potency 28183.8 nM None
Homo sapiens HaCaT IC50 50000.0 nM 10.1016/j.ejmech.2015.07.031
Homo sapiens HeLa IC50 21320.0 nM 10.1016/j.ejmech.2015.07.031
Homo sapiens HepG2 Potency 8912.5 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 56234.1 nM None
Homo sapiens MCF7 IC50 18240.0 nM 10.1016/j.ejmech.2015.07.031
Homo sapiens Mothers against decapentaplegic homolog 3 Potency 35481.3 nM None
Homo sapiens TAR DNA-binding protein 43 Potency 15848.9 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 20596.2 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 29092.9 nM None
Influenza A virus Nonstructural protein 1 Potency 3548.1 nM None
Photinus pyralis Luciferin 4-monooxygenase Potency 11995.5 nM None
Plasmodium falciparum Plasmodium falciparum Potency 5221.3 nM None
Plasmodium falciparum Plasmodium falciparum Potency 18526.0 nM None
None Unchecked Potency 6309.6 nM None

Metabolism Information