methyl 2,3-dioxo-1H-indole-7-carboxylate
AlkaPlorer ID: AK269074
Synonym: None
IUPAC Name: methyl 2,3-dioxo-1H-indole-7-carboxylate
Structure
SMILES: COC(=O)C1=CC=CC2=C1NC(=O)C2=O
InChI: InChI=1S/C10H7NO4/c1-15-10(14)6-4-2-3-5-7(6)11-9(13)8(5)12/h2-4H,1H3,(H,11,12,13)
InChIKey: BKMLLFWFPNUDNF-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 205.169
TPSA？: 72.47
MolLogP？: 0.6079999999999999
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Giardia intestinalis | Putative fructose-1,6-bisphosphate aldolase | Potency | 14091.9 | nM | None |
| Homo sapiens | DNA polymerase eta | Potency | 89125.1 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 14125.4 | nM | None |
| Homo sapiens | Geminin | Potency | 18356.4 | nM | None |
| Homo sapiens | Geminin | Potency | 29092.9 | nM | None |
| Homo sapiens | Glycoprotein hormones alpha chain | Potency | 11220.2 | nM | None |
| Homo sapiens | HEK293 | IC50 | 67615.0 | nM | None |
| Homo sapiens | HEK293 | Potency | 15848.9 | nM | None |
| Homo sapiens | Mothers against decapentaplegic homolog 3 | Potency | 31622.8 | nM | None |
| Homo sapiens | Nuclear receptor subfamily 0 group B member 1 | IC50 | 67615.0 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 20596.2 | nM | None |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 1 | Potency | 28183.8 | nM | None |
| None | Unchecked | Potency | 36.6 | nM | None |
| None | Unchecked | Potency | 15848.9 | nM | None |