morphinan, 17-methyl-
AlkaPlorer ID: AK276717
Synonym: None
IUPAC Name: 17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6-triene
Structure
SMILES: CN1CCC23CCCCC2C1CC1=CC=CC=C13
InChI: InChI=1S/C17H23N/c1-18-11-10-17-9-5-4-8-15(17)16(18)12-13-6-2-3-7-14(13)17/h2-3,6-7,15-16H,4-5,8-12H2,1H3
InChIKey: IHBSVVZENGBQDY-UHFFFAOYSA-N
Reference
Terpenoids from<i>Euphorbia pedroi</i>as Multidrug-Resistance Reversers
PubChem CID: 617841
CAS: 3882-38-0
SuperNatural Ⅲ: SN0145445
COCONUT: CNP0297881
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 241.378
TPSA？: 3.24
MolLogP？: 3.3748000000000022
Number of H-Donors: 0
Number of H-Acceptors: 1
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Glutamate [NMDA] receptor | IC50 | 1000.0 | nM | 10.1021/jm00100a019 |
| Homo sapiens | Glutamate [NMDA] receptor | IC50 | 1700.0 | nM | 10.1021/jm00100a019 |
| Rattus norvegicus | Glutamate NMDA receptor | IC50 | 1300.0 | nM | 10.1021/jm00100a019 |
| Rattus norvegicus | Glutamate NMDA receptor | IC50 | nan | nM | 10.1021/jm00100a019 |
| Rattus norvegicus | Glutamate NMDA receptor | Inhibition | 53.0 | % | 10.1021/jm00100a019 |
| Rattus norvegicus | Rattus norvegicus | Protection | 0.0 | % | 10.1021/jm00100a019 |