6-Amino-4,5-dihydroxy-3-piperidinecarboxylic acid; (3S,4S,5R,6S)-form, N-Ac
AlkaPlorer ID: AK285186
Synonym: Siastatin B, A 72363B, Antibiotic A 72363B
IUPAC Name: 6-acetamido-4,5-dihydroxypiperidine-3-carboxylic acid
Structure
SMILES: CC(O)=NC1NCC(C(=O)O)C(O)C1O
InChI: InChI=1S/C8H14N2O5/c1-3(11)10-7-6(13)5(12)4(2-9-7)8(14)15/h4-7,9,12-13H,2H2,1H3,(H,10,11)(H,14,15)
InChIKey: DQTKLICLJUKNCG-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces verticillus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 218.209
TPSA？: 122.38
MolLogP？: -1.6852999999999991
Number of H-Donors: 5
Number of H-Acceptors: 5
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Heparanase | IC50 | 12000.0 | nM | 10.1016/j.bmc.2013.01.033 |