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2-Amino-2-phenylacetic acid; (±)-form

AlkaPlorer ID: AK287106

Synonym: None

IUPAC Name: 2-amino-2-phenylacetic acid

Structure

SMILES: NC(C(=O)O)C1=CC=CC=C1

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InChI: InChI=1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)

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InChIKey: ZGUNAGUHMKGQNY-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Homo sapiens Homo Hominidae Primates Mammalia Chordata Metazoa Eukaryota

Properties Information

Molecule Weight: 151.165

TPSA？: 63.32000000000001

MolLogP？: 0.7709999999999999

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Rattus norvegicus Pyruvate dehydrogenase kinase PDH active/PDH total 87.0 % 10.1021/jm00136a009
Rattus norvegicus Pyruvate dehydrogenase kinase Stimulation 10.0 % 10.1021/jm00136a009
Rattus norvegicus Rattus norvegicus PDH active/PDH total 13.0 % 10.1021/jm00136a009
Rattus norvegicus Rattus norvegicus Stimulation 90.0 % 10.1021/jm00136a009
None Unchecked IC50 nan None 10.1128/aac.00392-07

Metabolism Information

AKRT ID Reaction Reaction Link ID
AKRT002304 CC(=O)NC(C(=O)O)c1ccccc1>>NC(C(=O)O)c1ccccc1 enzymemap_76450
AKRT006946 CC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.NC(C(=O)O)c1ccccc1>>CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1 enzymemap_52969
AKRT006958 CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1>>NC(C(=O)O)c1ccccc1 enzymemap_52969
AKRT015573 N#CC(N)c1ccccc1>>NC(C(=O)O)c1ccccc1 enzymemap_79418
AKRT017347 NC(C(=O)O)c1ccccc1>>O=C(O)C(=O)c1ccccc1 enzymemap_21882
AKRT022624 O=C(O)C(=O)c1ccccc1>>NC(C(=O)O)c1ccccc1 enzymemap_21865