Antibiotic GE 2270; Antibiotic GE 2270B2
AlkaPlorer ID: AK288438
Synonym: GE 2270B2
IUPAC Name: 1-[2-[2-[35-[hydroxy(phenyl)methyl]-21,28-dimethyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25-propan-2-yl-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decazaheptacyclo[34.2.1.12,5.112,15.119,22.126,29.06,11]tritetraconta-1(38),2(43),4,6(11),7,9,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl]-1,3-thiazol-4-yl]-4,5-dihydro-1,3-oxazole-4-carbonyl]pyrrolidine-2-carboxamide
Structure
SMILES: CN=C(O)CC1N=C(O)C2=CSC(=N2)C2=CC=C(C3=NC(C4=NC(C(=O)N5CCCC5C(=N)O)CO4)=CS3)N=C2C2=CSC(=N2)C2=CSC(=N2)C(C(O)C2=CC=CC=C2)N=C(O)CN=C(O)C2=C(C)SC(=N2)C(C(C)C)N=C(O)C2=C(C)SC1=N2
InChI: InChI=1S/C55H53N15O9S6/c1-23(2)38-54-69-39(24(3)85-54)46(76)58-17-37(72)66-42(43(73)26-10-7-6-8-11-26)53-65-34(22-83-53)51-62-31(19-81-51)41-27(49-63-32(20-80-49)45(75)60-29(16-36(71)57-5)52-68-40(25(4)84-52)47(77)67-38)13-14-28(59-41)50-64-33(21-82-50)48-61-30(18-79-48)55(78)70-15-9-12-35(70)44(56)74/h6-8,10-11,13-14,19-23,29-30,35,38,42-43,73H,9,12,15-18H2,1-5H3,(H2,56,74)(H,57,71)(H,58,76)(H,60,75)(H,66,72)(H,67,77)
InChIKey: UHWVQMFJEVJYGL-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Planobispora rosea | Planobispora | Streptosporangiaceae | Streptosporangiales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 1260.5269999999996
TPSA？: 359.39
MolLogP？: 10.55071
Number of H-Donors: 8
Number of H-Acceptors: 23
RingCount: 11
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|