Antibiotic GE 2270; Antibiotic GE 2270D2
AlkaPlorer ID: AK288443
Synonym: GE 2270D2
IUPAC Name: 1-[2-[2-[28-(hydroxymethyl)-35-[hydroxy(phenyl)methyl]-21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25-propan-2-yl-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decazaheptacyclo[34.2.1.12,5.112,15.119,22.126,29.06,11]tritetraconta-1(38),2(43),4,6(11),7,9,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl]-1,3-thiazol-4-yl]-4,5-dihydro-1,3-oxazole-4-carbonyl]pyrrolidine-2-carboxamide
Structure
SMILES: CN=C(O)CC1N=C(O)C2=CSC(=N2)C2=CC=C(C3=NC(C4=NC(C(=O)N5CCCC5C(=N)O)CO4)=CS3)N=C2C2=CSC(=N2)C2=CSC(=N2)C(C(O)C2=CC=CC=C2)N=C(O)CN=C(O)C2=C(CO)SC(=N2)C(C(C)C)N=C(O)C2=C(C)SC1=N2
InChI: InChI=1S/C55H53N15O10S6/c1-23(2)38-54-69-41(35(17-71)86-54)46(77)58-16-37(73)66-42(43(74)25-9-6-5-7-10-25)53-65-33(22-84-53)51-62-30(19-82-51)40-26(49-63-31(20-81-49)45(76)60-28(15-36(72)57-4)52-68-39(24(3)85-52)47(78)67-38)12-13-27(59-40)50-64-32(21-83-50)48-61-29(18-80-48)55(79)70-14-8-11-34(70)44(56)75/h5-7,9-10,12-13,19-23,28-29,34,38,42-43,71,74H,8,11,14-18H2,1-4H3,(H2,56,75)(H,57,72)(H,58,77)(H,60,76)(H,66,73)(H,67,78)
InChIKey: OKGFXSMHEYOSSF-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Planobispora rosea | Planobispora | Streptosporangiaceae | Streptosporangiales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 1276.5259999999996
TPSA？: 379.62
MolLogP？: 9.73459
Number of H-Donors: 9
Number of H-Acceptors: 24
RingCount: 11
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|