Antibiotic TAN 1120
AlkaPlorer ID: AK288753
Synonym: TAN 1120
IUPAC Name: 9-acetyl-6,9,11-trihydroxy-7-[[5-hydroxy-2-(2-hydroxypropyl)-4,10-dimethyl-4,5,6,6a,7,8,10,10a-octahydropyrano[3,4-d][1,3,6]dioxazocin-8-yl]oxy]-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Structure
SMILES: COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(CC(O)(C(C)=O)CC3OC3CC4NC(O)C(C)OC(CC(C)O)OC4C(C)O3)C(O)=C1C2=O
InChI: InChI=1S/C34H41NO13/c1-13(36)9-22-46-15(3)33(42)35-19-10-23(45-14(2)32(19)48-22)47-21-12-34(43,16(4)37)11-18-25(21)31(41)27-26(29(18)39)28(38)17-7-6-8-20(44-5)24(17)30(27)40/h6-8,13-15,19,21-23,32-33,35-36,39,41-43H,9-12H2,1-5H3
InChIKey: IYMKZHJAGBHDOV-UHFFFAOYSA-N
Reference
TAN-1120, a new anthracycline with potent angiostatic activity.
PubChem CID: 131380
CAS: 131443-34-0
LOTUS: LTS0160401
COCONUT: CNP0193788.2
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces triangulatus | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 671.6960000000003
TPSA？: 210.54
MolLogP？: 1.518199999999999
Number of H-Donors: 6
Number of H-Acceptors: 14
RingCount: 6
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|