Molecule

Azicemicin A

AlkaPlorer ID: AK290004

Synonym: None

IUPAC Name: 3,7,8,10,12b-pentahydroxy-9,12-dimethoxy-3-(1-methylaziridin-2-yl)-2,4,4a,5-tetrahydrobenzo[a]anthracene-1,6-dione

Structure

SMILES: COC1=C(O)C=C2C(OC)=C3C(=C(O)C2=C1O)C(=O)CC1CC(O)(C2CN2C)CC(=O)C31O

InChI: InChI=1S/C23H25NO9/c1-24-8-13(24)22(30)6-9-4-11(25)16-17(23(9,31)14(27)7-22)20(32-2)10-5-12(26)21(33-3)19(29)15(10)18(16)28/h5,9,13,26,28-31H,4,6-8H2,1-3H3

InChIKey: FGEKNLXFZXJGOO-UHFFFAOYSA-N

Reference

Azicemicins A and B, New Antimicrobial Agents Produced by Amycolatopsis. II. Structure Determination.

PubChem CID: 160393

CAS: 154163-93-6

LOTUS: LTS0070204

COCONUT: CNP0200501.4

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NPAtlas: NPA016564

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Amycolatopsis sp.	Amycolatopsis	Pseudonocardiaceae	Pseudonocardiales	Actinomycetes	Actinomycetota	None	Bacteria

Properties Information

Molecule Weight: 459.4510000000003

TPSA？: 156.76

MolLogP？: 0.7719999999999996

Number of H-Donors: 5

Number of H-Acceptors: 10

RingCount: 5

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Bacillus anthracis	Bacillus anthracis	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Bacillus cereus	Bacillus cereus	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Bacillus subtilis	Bacillus subtilis	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Corynebacterium bovis	Corynebacterium bovis	MIC	25.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Escherichia coli	Escherichia coli	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Escherichia coli	Escherichia coli	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Klebsiella pneumoniae	Klebsiella pneumoniae	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Micrococcus luteus	Micrococcus luteus	MIC	12.5	ug.mL-1	10.1016/j.ejmech.2009.05.013
Micrococcus luteus	Micrococcus luteus	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Mycolicibacterium smegmatis	Mycolicibacterium smegmatis	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Mycolicibacterium vaccae	Mycolicibacterium vaccae	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Proteus mirabilis	Proteus mirabilis	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Proteus vulgaris	Proteus vulgaris	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Providencia rettgeri	Providencia rettgeri	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Salmonella enterica subsp. enterica	Salmonella enterica subsp. enterica	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Shigella dysenteriae	Shigella dysenteriae	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Shigella flexneri	Shigella flexneri	MIC	50.0	ug.mL-1	10.1016/j.ejmech.2009.05.013
Staphylococcus aureus	Staphylococcus aureus	MIC	100.0	ug.mL-1	10.1016/j.ejmech.2009.05.013