Brevicolline; (±)-form
AlkaPlorer ID: AK291000
Synonym: None
IUPAC Name: 1-methyl-4-(1-methylpyrrolidin-2-yl)-9H-pyrido[3,4-b]indole
Structure
SMILES: CC1=NC=C(C2CCCN2C)C2=C1NC1=CC=CC=C12
InChI: InChI=1S/C17H19N3/c1-11-17-16(12-6-3-4-7-14(12)19-17)13(10-18-11)15-8-5-9-20(15)2/h3-4,6-7,10,15,19H,5,8-9H2,1-2H3
InChIKey: DIZAFWUMCZPYGF-UHFFFAOYSA-N
Reference
1,4-Substituted b-Carbolines from Carex brevicollis DC
PubChem CID: 5748597
CAS: 20069-02-7
LOTUS: LTS0136637
COCONUT: CNP0359411.1
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Carex brevicollis | Carex | Cyperaceae | Poales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 265.36
TPSA？: 31.92
MolLogP？: 3.791220000000002
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Bacillus subtilis | Bacillus subtilis | IZ | 12.5 | mm | 10.1021/np50028a027 |
| Candida albicans | Candida albicans | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Candida albicans | Candida albicans | IZ | 9.5 | mm | 10.1021/np50028a027 |
| Cricetulus griseus | CHO | Activity | 0.0 | % | 10.1021/np50028a027 |
| Cricetulus griseus | CHO | Activity | 5.5 | % | 10.1021/np50028a027 |
| Cricetulus griseus | CHO | Activity | 37.1 | % | 10.1021/np50028a027 |
| Cricetulus griseus | CHO | Activity | 56.0 | % | 10.1021/np50028a027 |
| Cricetulus griseus | CHO | Activity | nan | None | 10.1021/np50028a027 |
| Enterococcus faecalis | Enterococcus faecalis | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Enterococcus faecalis | Enterococcus faecalis | IZ | 14.0 | mm | 10.1021/np50028a027 |
| Escherichia coli | Escherichia coli | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Escherichia coli | Escherichia coli | IZ | 15.5 | mm | 10.1021/np50028a027 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | IZ | 13.0 | mm | 10.1021/np50028a027 |
| Pseudomonas fluorescens | Pseudomonas fluorescens | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Pseudomonas fluorescens | Pseudomonas fluorescens | IZ | 7.0 | mm | 10.1021/np50028a027 |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | IZ | 7.0 | mm | 10.1021/np50028a027 |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 0.0 | mm | 10.1021/np50028a027 |
| Staphylococcus aureus | Staphylococcus aureus | IZ | 15.3 | mm | 10.1021/np50028a027 |