Nα-Cinnamoylhistamine; (Z)-3H-form
AlkaPlorer ID: AK292509
Synonym: None
IUPAC Name: (E)-N-[2-(1H-imidazol-5-yl)ethyl]-3-phenylprop-2-enamide
Structure
SMILES: OC(/C=C/C1=CC=CC=C1)=NCCC1=CN=CN1
InChI: InChI=1S/C14H15N3O/c18-14(7-6-12-4-2-1-3-5-12)16-9-8-13-10-15-11-17-13/h1-7,10-11H,8-9H2,(H,15,17)(H,16,18)/b7-6+
InChIKey: HCENGXRZXKAJLN-VOTSOKGWSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Itoa orientalis | Itoa | Salicaceae | Malpighiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Clitocybe rhizophora | Clitocybe | Clitocybaceae | Agaricales | Agaricomycetes | Basidiomycota | Fungi | Eukaryota |
| Myrianthus arboreus | Myrianthus | Urticaceae | Rosales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 241.294
TPSA？: 61.27
MolLogP？: 2.6221000000000005
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Geminin | Potency | 20596.2 | nM | None |
| Homo sapiens | Lethal(3)malignant brain tumor-like protein 1 | Potency | 31622.8 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 10322.5 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 446.7 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 414.7 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 5221.3 | nM | None |
| None | Unchecked | Potency | 11582.1 | nM | None |
| None | Unchecked | Potency | 35481.3 | nM | None |