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Colchatetralene

AlkaPlorer ID: AK292820

Synonym: Alkaloid KL 4, KL 4

IUPAC Name: N-(1,2,3-trihydroxy-6-methyl-9-oxo-6,11a-dihydro-5H-cyclohepta[a]naphthalen-6a-yl)acetamide

Structure

SMILES: CC(=O)NC12C=CC(=O)C=CC1C1=C(O)C(O)=C(O)C=C1CC2C

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InChI: InChI=1S/C18H19NO5/c1-9-7-11-8-14(22)16(23)17(24)15(11)13-4-3-12(21)5-6-18(9,13)19-10(2)20/h3-6,8-9,13,22-24H,7H2,1-2H3,(H,19,20)

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InChIKey: WLVIZDWMIUYCQM-UHFFFAOYSA-N

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Reference

PubChem CID: 71522115

COCONUT: CNP0127210.1

Source

Species Genus Family Order Class Phylum Kingdom Domain
Gloriosa superba Gloriosa Colchicaceae Liliales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 329.3520000000001

TPSA？: 106.86

MolLogP？: 1.6491999999999998

Number of H-Donors: 4

Number of H-Acceptors: 5

RingCount: 3

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Bacillus subtilis Bacillus subtilis IZ 17.5 mm 10.1007/s00044-012-0032-z
Bacillus subtilis Bacillus subtilis MIC 50.0 ug.mL-1 10.1007/s00044-012-0032-z
Candida albicans Candida albicans IZ 18.9 mm 10.1007/s00044-012-0032-z
Candida albicans Candida albicans MIC 12.5 ug.mL-1 10.1007/s00044-012-0032-z
Chlorocebus aethiops CV-1 GI 13.0 % 10.1007/s00044-012-0032-z
Chlorocebus aethiops CV-1 GI 19.0 % 10.1007/s00044-012-0032-z
Chlorocebus aethiops CV-1 GI 35.0 % 10.1007/s00044-012-0032-z
Escherichia coli Escherichia coli IZ 13.3 mm 10.1007/s00044-012-0032-z
Escherichia coli Escherichia coli MIC 100.0 ug.mL-1 10.1007/s00044-012-0032-z
Goffeauzyma gastrica Goffeauzyma gastrica IZ 15.3 mm 10.1007/s00044-012-0032-z
Goffeauzyma gastrica Goffeauzyma gastrica MIC 50.0 ug.mL-1 10.1007/s00044-012-0032-z
Homo sapiens A549 GI 23.0 % 10.1007/s00044-012-0032-z
Homo sapiens MCF7 GI 26.0 % 10.1007/s00044-012-0032-z
Homo sapiens MCF7 GI 33.0 % 10.1007/s00044-012-0032-z
Homo sapiens MCF7 GI 52.0 % 10.1007/s00044-012-0032-z
Homo sapiens MCF7 GI 70.0 % 10.1007/s00044-012-0032-z
Homo sapiens MCF7 IC50 50.0 ug.mL-1 10.1007/s00044-012-0032-z
Homo sapiens OVCAR-5 GI 9.0 % 10.1007/s00044-012-0032-z
Homo sapiens OVCAR-5 GI 17.0 % 10.1007/s00044-012-0032-z
Homo sapiens OVCAR-5 GI 33.0 % 10.1007/s00044-012-0032-z
Homo sapiens OVCAR-5 GI 43.0 % 10.1007/s00044-012-0032-z
Homo sapiens THP-1 GI 48.0 % 10.1007/s00044-012-0032-z
Homo sapiens THP-1 GI 55.0 % 10.1007/s00044-012-0032-z
Homo sapiens THP-1 GI 67.0 % 10.1007/s00044-012-0032-z
Homo sapiens THP-1 GI 80.0 % 10.1007/s00044-012-0032-z
Homo sapiens THP-1 IC50 30.0 ug.mL-1 10.1007/s00044-012-0032-z
Pseudomonas aeruginosa Pseudomonas aeruginosa IZ 11.9 mm 10.1007/s00044-012-0032-z
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 100.0 ug.mL-1 10.1007/s00044-012-0032-z
Saccharomyces cerevisiae Saccharomyces cerevisiae IZ 16.9 mm 10.1007/s00044-012-0032-z
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 25.0 ug.mL-1 10.1007/s00044-012-0032-z
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi GI nan None 10.1007/s00044-012-0032-z
Salmonella enterica subsp. enterica serovar Typhi Salmonella typhi MIC nan None 10.1007/s00044-012-0032-z
Staphylococcus aureus Staphylococcus aureus IZ 15.7 mm 10.1007/s00044-012-0032-z
Staphylococcus aureus Staphylococcus aureus MIC 25.0 ug.mL-1 10.1007/s00044-012-0032-z

Metabolism Information