Cryptophycin 29; Dechloro, 7R,8R-epoxide
AlkaPlorer ID: AK293290
Synonym: Arenastatin A, Cryptophycin 24
IUPAC Name: 10-[(4-methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[1-(3-phenyloxiran-2-yl)ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
Structure
SMILES: COC1=CC=C(CC2N=C(O)C=CCC(C(C)C3OC3C3=CC=CC=C3)OC(=O)C(CC(C)C)OC(=O)CCN=C2O)C=C1
InChI: InChI=1S/C34H42N2O8/c1-21(2)19-28-34(40)43-27(22(3)31-32(44-31)24-9-6-5-7-10-24)11-8-12-29(37)36-26(33(39)35-18-17-30(38)42-28)20-23-13-15-25(41-4)16-14-23/h5-10,12-16,21-22,26-28,31-32H,11,17-20H2,1-4H3,(H,35,39)(H,36,37)
InChIKey: GPUHMLPBKTYERL-UHFFFAOYSA-N
Reference
Arenastatin A, a potent cytotoxic depsipeptide from the okinawan marine sponge Dysidea arenaria
PubChem CID: 72808952
LOTUS: LTS0180383
COCONUT: CNP0169337.4
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Nostoc sp. ATCC 53789 | Nostoc | Nostocaceae | Nostocales | Cyanophyceae | Cyanobacteriota | None | Bacteria |
| Dysidea arenaria | Dysidea | Dysideidae | Dictyoceratida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 606.7160000000002
TPSA？: 139.54000000000002
MolLogP？: 5.515200000000005
Number of H-Donors: 2
Number of H-Acceptors: 8
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|