2'-Deoxycytidine; β-L-form
AlkaPlorer ID: AK294811
Synonym: Torcitabine, Epcitabine, NV 02C
IUPAC Name: 4-amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Structure
SMILES: NC1=NC(=O)N(C2CC(O)C(CO)O2)C=C1
InChI: InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)
InChIKey: CKTSBUTUHBMZGZ-UHFFFAOYSA-N
Reference
Purine and Nucleoside Metabolites from the Antarctic Sponge <i>Isodictya erinacea</i>
PubChem CID: 637
LOTUS: LTS0263788
COCONUT: CNP0146400.6
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Isodictya erinacea | Isodictya | Isodictyidae | Poecilosclerida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 227.22
TPSA？: 110.6
MolLogP？: -1.5338
Number of H-Donors: 3
Number of H-Acceptors: 7
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli K-12 | Beta-lactamase AmpC | Potency | 19952.6 | nM | None |
| Giardia intestinalis | Putative fructose-1,6-bisphosphate aldolase | Potency | 10000.0 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 100000.0 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 9285.0 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 14715.7 | nM | None |