2,3-Dichloro-4-nitro-1H-pyrrole
AlkaPlorer ID: AK295519
Synonym: Pyrrolomycin A, SF 2080A, Antibiotic SF 2080A
IUPAC Name: 2,3-dichloro-4-nitro-1H-pyrrole
Structure
SMILES: O=[N+]([O-])C1=CNC(Cl)=C1Cl
InChI: InChI=1S/C4H2Cl2N2O2/c5-3-2(8(9)10)1-7-4(3)6/h1,7H
InChIKey: CDHAYBUDIPNGGJ-UHFFFAOYSA-N
Reference
Pyrrolomycins C,D and E,new members of pyrrolomycins.
PubChem CID: 133275
CAS: 79763-01-2
LOTUS: LTS0131695
{NPAtlas: NPA020404
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces sp. | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 180.978
TPSA？: 58.93
MolLogP？: 2.2297
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Aspergillus fumigatus | Aspergillus fumigatus | MIC | 25.0 | ug.mL-1 | 10.1021/jm00386a019 |
| Candida albicans | Candida albicans | MIC | 100.0 | ug.mL-1 | 10.1021/jm00386a019 |
| Cryptococcus neoformans | Cryptococcus neoformans | MIC | 25.0 | ug.mL-1 | 10.1021/jm00386a019 |
| Trichophyton benhamiae | Trichophyton benhamiae | MIC | 6.25 | ug.mL-1 | 10.1021/jm00386a019 |
| Trichophyton interdigitale | Trichophyton interdigitale | MIC | 3.13 | ug.mL-1 | 10.1021/jm00386a019 |