3,4-Dihydro-4,5-dihydroxy-3-methoxy-4-(4-methoxyphenyl)-2(1H)-quinolinone; 5-Deoxy
AlkaPlorer ID: AK295716
Synonym: 3,4-Dihydro-4-hydroxy-3-methoxy-4-(4-methoxyphenyl)-2(1H)-quinolinone, Peneciraistin F, Quinolinone A
IUPAC Name: 4-hydroxy-3-methoxy-4-(4-methoxyphenyl)-1,3-dihydroquinolin-2-one
Structure
SMILES: COC1=CC=C(C2(O)C3=CC=CC=C3N=C(O)C2OC)C=C1
InChI: InChI=1S/C17H17NO4/c1-21-12-9-7-11(8-10-12)17(20)13-5-3-4-6-14(13)18-16(19)15(17)22-2/h3-10,15,20H,1-2H3,(H,18,19)
InChIKey: VCKUOSKDXLTBDG-UHFFFAOYSA-N
Reference
New Dihydroquinolinone Toxic to<i>Artemia salina</i>Produced by<i>Penicillium</i>sp. NTC-47
PubChem CID: 23843957
LOTUS: LTS0024595
COCONUT: CNP0169932.5
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Penicillium | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
| Penicillium raistrickii | Penicillium | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
| Penicillium sp. | Penicillium | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
| None | Penicillium | Aspergillaceae | Eurotiales | Eurotiomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 299.3260000000001
TPSA？: 71.28
MolLogP？: 2.5477000000000007
Number of H-Donors: 2
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | Inhibition | 4.0 | % | 10.6019/CHEMBL4888484 |
| Plasmodium falciparum | Plasmodium falciparum | Z score | -0.66 | None | 10.6019/CHEMBL4888484 |