1,3-Dihydro-3-hydroxy-3-(2-oxopropyl)-2H-indol-2-one; (ξ)-form
AlkaPlorer ID: AK295837
Synonym: None
IUPAC Name: 3-hydroxy-3-(2-oxopropyl)-1H-indol-2-one
Structure
SMILES: CC(=O)CC1(O)C(=O)NC2=CC=CC=C21
InChI: InChI=1S/C11H11NO3/c1-7(13)6-11(15)8-4-2-3-5-9(8)12-10(11)14/h2-5,15H,6H2,1H3,(H,12,14)
InChIKey: CBMTTXBZZZABGG-UHFFFAOYSA-N
Reference
Flavonoids of the flowers of Silybum marianum
PubChem CID: 36460
CAS: 33417-17-3
COCONUT: CNP0124963.2
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Shewanella piezotolerans | Shewanella | Shewanellaceae | Alteromonadales | Gammaproteobacteria | Pseudomonadota | None | Bacteria |
Properties Information
Molecule Weight: 205.213
TPSA？: 66.39999999999999
MolLogP？: 0.8053999999999999
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 50118.7 | nM | None |
| Homo sapiens | Histone acetyltransferase GCN5 | Potency | 707.9 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 827.5 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 18526.0 | nM | None |