1-(3,4-Dihydroxyphenyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol; (R)-form
AlkaPlorer ID: AK296430
Synonym: Alternamine A
IUPAC Name: 1-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Structure
SMILES: OC1=C(O)C=C(C2NCCC3=CC(O)=C(O)C=C32)C=C1
InChI: InChI=1S/C15H15NO4/c17-11-2-1-9(6-12(11)18)15-10-7-14(20)13(19)5-8(10)3-4-16-15/h1-2,5-7,15-20H,3-4H2
InChIKey: BGTFAVHCDMORNO-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Portulaca oleracea | Portulaca | Portulacaceae | Caryophyllales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
| Alternanthera littoralis | Alternanthera | Amaranthaceae | Caryophyllales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 273.28799999999995
TPSA？: 92.95
MolLogP？: 1.7440999999999995
Number of H-Donors: 5
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Alpha-1b adrenergic receptor | Activity | 16.6 | % | 10.1021/acs.jnatprod.9b00418 |
| Homo sapiens | Beta-1 adrenergic receptor | Activity | nan | None | 10.1021/acs.jnatprod.9b00418 |
| Homo sapiens | Beta-2 adrenergic receptor | Activity | nan | None | 10.1021/acs.jnatprod.9b00418 |